Salmonella enterica typhi Essay -- Medical Health Biology Essays

Salmonella enterica typhiIntroduction worldwide, enteric fever fever affects around 17 million people annually, causing nearly 600,000 deaths. The causative agent, Salmonella enterica typhi (referred to as Salmonella typhi from now on), is an obligate parasite that has no known natural informant outside of humanitys. Little is known about the historical emergence of human S. typhi infections, however it is thought to have caused the deaths of many famous figures such as British author and poet Rudyard Kipling, the inventor of the airplane, Wilbur Wright, and the Greek Empires black lovage the Great. The earliest recorded epidemic occurred in Jamestown, VA where it is thought that 6,000 people died of typhoid fever in the early 17th Century. This disease is rare in the United States and developed nations, but always poses the risk of emergence. History primarily isolated in 1880 by Karl J. Erberth, S. typhi is a multi-organ pathogen that inhabits the lympathic tissues of the small intestine, liver, spleen, and bloodstream of give humans. It is not known to infect animals and is most common in develop countries with poor sanitary systems and lack of antibiotics, putting travelers to Asia, Latin America, and Africa in a high risk group. Of the 266 people infected in the United States in 2002, approximately 70% had traveled internationally within 6 weeks of the infringement of disease.Microbiological CharacteristicsThis gram-negative enteric bacillus belongs to the family Enterobacteriaceae. It is a motile, facultative anaerobe that is susceptible to several(prenominal)(a) antibiotics. Currently, 107 strains of this organism have been isolated, many containing varying metabolic characteristics, levels of virulence, and multi-drug r... ...asters have compromised sanitation. Although the relative incidence in the United States is very low, outbreaks and substantial epidemics still remain possible due to worldwide travel and unknowing carriers of the diseas e. The development of antibiotic treatments and several vaccines have presented the possibility of worldwide eradication. Until this is achieved, however, S. typhi and its characteristic typhoid fever result remain a threat for future epidemics.References CitedDennis Kunkel Microscopy, Inc. Health Canada MSDS of Infectious SubstancesWorld Health Organization Typhoid Fever Fact SheetCenters for indisposition Control and Prevention Typhoid Fever Disease InformationUniversity of Florida medical exam Micribiology and Infectious Diseases Department Salmonella typhi Info Wikipedia.org Typhoid Fever U. of Maryland aesculapian news Typhoid Fever